Gene information
Official symbol TXN
Official full name thioredoxin
Gene type protein-coding gene
Chromosome9q31.3
Alias symbolTRX
Resources
Entrez Gene 7295
HGNC HGNC:12435
Ensembl ENSG00000136810
Vega OTTHUMG00000020480
UCSC uc004bep.3
GO terms: 40 records
GO Description Category LogP Number of genes Detail
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0009314 response to radiation GO Biological Processes -9.77450393 26 More
GO:0009636 response to toxic substance GO Biological Processes -18.1818984 46 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0016209 antioxidant activity GO Molecular Functions -11.3593886 22 More
GO:0019725 cellular homeostasis GO Biological Processes -21.1508273 85 More
GO:0032147 activation of protein kinase activity GO Biological Processes -11.6086663 28 More
GO:0032148 activation of protein kinase B activity GO Biological Processes -8.71311579 12 More
GO:0032386 regulation of intracellular transport GO Biological Processes -4.43340887 15 More
GO:0032387 negative regulation of intracellular transport GO Biological Processes -2.91439773 5 More
GO:0033138 positive regulation of peptidyl-serine phosphorylation GO Biological Processes -6.77396219 11 More
GO:0033157 regulation of intracellular protein transport GO Biological Processes -4.35957871 12 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043388 positive regulation of DNA binding GO Biological Processes -12.0675836 19 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051099 positive regulation of binding GO Biological Processes -11.1715489 31 More
GO:0051101 regulation of DNA binding GO Biological Processes -9.69427751 24 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051224 negative regulation of protein transport GO Biological Processes -11.0190941 26 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090317 negative regulation of intracellular protein transport GO Biological Processes -2.62366605 4 More
GO:0097237 cellular response to toxic substance GO Biological Processes -13.7473733 28 More
GO:0098869 cellular oxidant detoxification GO Biological Processes -12.6410846 24 More
GO:1900407 regulation of cellular response to oxidative stress GO Biological Processes -21.4526227 33 More
GO:1901031 regulation of response to reactive oxygen species GO Biological Processes -8.30091899 13 More
GO:1902882 regulation of response to oxidative stress GO Biological Processes -20.0046302 33 More
GO:1903201 regulation of oxidative stress-induced cell death GO Biological Processes -18.4601079 28 More
GO:1903202 negative regulation of oxidative stress-induced cell death GO Biological Processes -17.0330784 23 More
GO:1903206 negative regulation of hydrogen peroxide-induced cell death GO Biological Processes -7.13135320 9 More
GO:1903828 negative regulation of protein localization GO Biological Processes -8.86943289 30 More
GO:1904950 negative regulation of establishment of protein localization GO Biological Processes -11.4813166 27 More
KEGG pathways: 3 records
KEGG Description Category LogP Number of genes Detail
hsa04621 NOD-like receptor signaling pathway KEGG Pathway -7.63493695 15 More
hsa05132 Salmonella infection KEGG Pathway -7.42305681 17 More
hsa05418 Fluid shear stress and atherosclerosis KEGG Pathway -23.1665561 27 More
Drug-Gene interaction
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Related drugs: 4 records
Related studies: 4 records
Molecular factor Omics type Application Objective MI type Reference
thioredoxin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Miyamoto S et al. Am Heart J. 2003
thioredoxin proteomics reperfusion failure[prognosis (bad)] acute ST elevation myocardial infarction Soejima H et al. Clin Cardiol. 2003
thioredoxin proteomics myocardial injury[prognosis (bad)] acute myocardial infarction Shim YK et al. J Korean Med Sci. 2012
thioredoxin proteomics myocardial injury[prognosis (bad)] acute myocardial infarction Shim YK et al. J Korean Med Sci. 2012
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